Green synthesis of silver nanoparticles from extracts of Pechuel-loeschea leubnitziae: Their antiproliferative activity against the U87 cell line select="/dri:document/dri:meta/dri:pageMeta/dri:metadata[@element='title']/node()"/>

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dc.contributor.author Mofolo, Motshewa Justina
dc.date.accessioned 2021-08-06T06:41:41Z
dc.date.available 2021-08-06T06:41:41Z
dc.date.issued 2020
dc.identifier.uri http://hdl.handle.net/11070/3049
dc.description.abstract The application of green chemistry for the synthesis of nanoparticles is said to be environmentally friendly and cost efficient. The paper reports on the cell anti-proliferative activity of Pechuelloeschea leubnitziae, synthesis of silver nanoparticles using P. leubnitziae and characterization. The UV–vis spectroscopy confirmed presence of a peak at 400 nm, and Fourier-transform infrared spectroscopy confirmed the presence of peaks from 700-4000 cm 1 correlating to AgNPs. Presence of silver, carbon and oxygen was confirmed by X-ray photoelectron spectroscopy and Energydispersive X-ray spectroscopy. Transmission electron microscopy showed a uniform spherical particle in the size of 100 nm, and scanning electron microscope showed spherical particles at a magnification of 100 mm. The extracts and the synthesized AgNPs were tested for cytotoxicity and anti-cancer activity against the Vero and U87 glioma cell lines. The results for both cell lines indicated that dichloromethane extract and AgNPs were cytotoxic and had potential anticancer properties. en_US
dc.language.iso en en_US
dc.publisher Taylor & Francis en_US
dc.subject Inhibition en_US
dc.subject U87 glioma en_US
dc.subject Cytotoxicity en_US
dc.subject Silver nanoparticles en_US
dc.title Green synthesis of silver nanoparticles from extracts of Pechuel-loeschea leubnitziae: Their antiproliferative activity against the U87 cell line en_US
dc.type Article en_US


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