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Likius, Daniel S. 2014-02-07T14:08:10Z 2014-02-07T14:08:10Z 2009 http://hdl.handle.net/11070/453 F004-199299999999999 A thesis submitted in partial fulfilmenty of the requirements for the Degree of Master of Science Abstract provided by author The synthesis and characterization,spectroscopic, and biological studies of 2-acetylferrocenyl-4-phenylthiosemicarbazone, 2-acetylferrocenyl-4-methylthiosemicarbazone,2-acetylpyridine-2-thiophenecarboxylsemicarbazone and 2-acetylferrocenyl-2-thiophenecarboxylsemicarbazone with copper(II) chloride are reported here. The ligands were synthesized by condensation reaction of appropriate carbonyl and amine compounds. The reactions were carried out in the presence of acetic acid. The complexes were characterized by means of Elemental Analysis (EA), Fourier Transform Infrared (FT-IR) spectroscopy, Nuclear Magnetic Resonance (1HNMR and 13CNMR) spectroscopy. The metal complexes and their corresponding ligands were tested against malaria parasites. It was found that the copper complexes synthesized are more biologically active then their corresponding ligands. Windhoek Namibia University of Namibia Master of Science xv, 80 p eng http://wwwisis.unam.na/theses/likius2009.pdf Copper compounds The Synthesis and characterization of copper(II) complexes containing thiosemicarbazone and semicarbazone ligands derived from Ferrocene and pyridyl fragments Thesis 3605open.access