Green synthesis of silver nanoparticles from extracts of Pechuel-loeschea leubnitziae: Their antiproliferative activity against the U87 cell line
| dc.contributor.author | Mofolo, Motshewa Justina | |
| dc.date.accessioned | 2021-08-06T06:41:41Z | |
| dc.date.available | 2021-08-06T06:41:41Z | |
| dc.date.issued | 2020 | |
| dc.description.abstract | The application of green chemistry for the synthesis of nanoparticles is said to be environmentally friendly and cost efficient. The paper reports on the cell anti-proliferative activity of Pechuelloeschea leubnitziae, synthesis of silver nanoparticles using P. leubnitziae and characterization. The UV–vis spectroscopy confirmed presence of a peak at 400 nm, and Fourier-transform infrared spectroscopy confirmed the presence of peaks from 700-4000 cm 1 correlating to AgNPs. Presence of silver, carbon and oxygen was confirmed by X-ray photoelectron spectroscopy and Energydispersive X-ray spectroscopy. Transmission electron microscopy showed a uniform spherical particle in the size of 100 nm, and scanning electron microscope showed spherical particles at a magnification of 100 mm. The extracts and the synthesized AgNPs were tested for cytotoxicity and anti-cancer activity against the Vero and U87 glioma cell lines. The results for both cell lines indicated that dichloromethane extract and AgNPs were cytotoxic and had potential anticancer properties. | en_US |
| dc.identifier.uri | http://hdl.handle.net/11070/3049 | |
| dc.language.iso | en | en_US |
| dc.publisher | Taylor & Francis | en_US |
| dc.subject | Inhibition | en_US |
| dc.subject | U87 glioma | en_US |
| dc.subject | Cytotoxicity | en_US |
| dc.subject | Silver nanoparticles | en_US |
| dc.title | Green synthesis of silver nanoparticles from extracts of Pechuel-loeschea leubnitziae: Their antiproliferative activity against the U87 cell line | en_US |
| dc.type | Article | en_US |